Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9076172 | 0.79 | HTR3A (0.55) | RAB9AKMT2AMAPTLMNAHTT | |
| Fumaric Acid SCHEMBL9050456 | 0.77 | HTR3A (0.43) | RAB9ANPC1KMT2AMAPTLMNA | |
| SCHEMBL6271791 | 0.76 | HTR3A (0.48) | RAB9ANPC1KMT2AMAPTLMNA | |
| SCHEMBL9049337 | 0.76 | HTR3A (0.48) | RAB9ANPC1KMT2AMAPTLMNA | |
| SCHEMBL9075286 | 0.73 | NPSR1 (0.37) | MAPTLMNACYP2C9ALDH1A1NPSR1 | |
| Fumaric Acid SCHEMBL9050462 | 0.73 | HTR3A (0.52) | RAB9ANPC1KMT2AMAPTLMNA | |
| SCHEMBL16585577 | 0.72 | HTR3A (0.58) | RAB9ANPC1KMT2AMAPTLMNA | |
| SCHEMBL9050459 | 0.67 | RAB9A (0.39) | RAB9ANPC1KMT2AMAPTLMNA | |
| Fumaric Acid SCHEMBL9050460 | 0.65 | SIRT1 (0.40) | KMT2AMAPTLMNAMEN1CYP1A2 | |
| Fumaric Acid SCHEMBL9050432 | 0.64 | HTR3A (0.40) | KMT2AMAPTMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496942-A | 5-HT3-RECEPTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| US-5344927-A | 5-HT3 antagonist | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |