Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.47 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | EBP | Q15125 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28108814 | 0.91 | ABCB1 (0.50) | ABCB1MGAMGAASIMGAM2 | |
| SCHEMBL21722716 | 0.84 | GAA (0.45) | ABCB1MEN1KMT2AMGAMGAA | |
| SCHEMBL1055709 | 0.82 | MGAM (0.45) | MGAMGAASIMGAM2 | |
| SCHEMBL4420078 | 0.80 | LIPE (0.47) | HTR1A | |
| SCHEMBL7511997 | 0.79 | HSD17B10 (0.58) | HTR1AADRA1DADRA1AADRA1BBCHE | |
| SCHEMBL9077431 | 0.79 | MTNR1A (0.49) | C5AR1 | |
| Hydrochloric Acid SCHEMBL9077573 | 0.79 | SIGMAR1 (0.69) | SIGMAR1EBPTMEM97 | |
| SCHEMBL19612479 | 0.77 | ABCB1 (0.53) | ABCB1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL19532378 | 0.77 | FFAR4 (0.49) | HTR1AADRA1DADRA1AADRA1BMGAM | |
| SCHEMBL2094271 | 0.76 | MAOB (0.59) | ABCB1HTR1AMEN1KMT2AMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5495046-A | PSYCHOLOGICAL DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0641766-A1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-08 | — | — | EP | disclosed |