Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988373 | 0.86 | TP53 (0.50) | LOXL2TP53TAAR1SLC6A2MAOA | |
| SCHEMBL28291474 | 0.86 | TP53 (0.50) | LOXL2TP53TAAR1SLC6A2MAOA | |
| SCHEMBL9076210 | 0.77 | LOXL2 (0.41) | LOXL2TP53TAAR1CYP2A6HTR2A | |
| SCHEMBL1728429 | 0.75 | CALM1 (0.50) | LOXL2TP53TAAR1CYP2A6HTR2A | |
| SCHEMBL11146025 | 0.75 | TP53 (0.39) | TP53SMN1; SMN2SIGMAR1 | |
| SCHEMBL27943101 | 0.73 | TP53 (0.46) | LOXL2TP53SMN1; SMN2SIGMAR1CALM1 | |
| SCHEMBL9075995 | 0.73 | LOXL2 (0.46) | LOXL2TP53TAAR1CYP2A6HTR2A | |
| Hydrochloric Acid SCHEMBL9074421 | 0.71 | LOXL2 (0.44) | LOXL2TP53TAAR1CYP2A6HTR2A | |
| SCHEMBL9346229 | 0.71 | ALDH1A1 (0.43) | TP53SLC6A2SLC6A4SLC6A3CYP1A2 | |
| SCHEMBL9350313 | 0.71 | ALDH1A1 (0.43) | TP53SLC6A2SLC6A4SLC6A3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532397-A | Substituted silyl alkylene amines | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-02 | — | — | US | disclosed |
| US-5529988-A | Substituted silyl alkylene amines | MERRELL PHARMACEUTICALS INC. (US) | 1996-06-25 | — | — | US | disclosed |
| US-5384312-A | Substituted silyl alkylene amines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-01-24 | — | — | US | disclosed |
| EP-0291787-B1 | Novel substituted silyl alkylene amines | MERRELL DOW PHARMA (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0291787-A1 | Novel substituted silyl alkylene amines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-11-23 | — | — | EP | disclosed |