SCHEMBL907778

SCHEMBL907778

c1ncnc(N2CCOCC2)n1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.52
KDM4E B2RXH2 2/20 0.46
GAA P10253 2/20 0.44
PIK3CA P42336 4/20 0.44
PIK3CD O00329 1/20 0.44
PIK3CB P42338 1/20 0.44
PIK3R1 P27986 3/20 0.43
MTOR P42345 3/20 0.43
MAPK1 P28482 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KMT2A Q03164 1/20 0.43
CNR2 P34972 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
TSHR P16473 1/20 0.41
PTK2 Q05397 1/20 0.41
MET P08581 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4328363 0.92 POLB (0.46) POLBKDM4EGAAPIK3CAPIK3CD
SCHEMBL9418619 0.83 SORD (0.50) POLBKDM4EGAASMN1; SMN2KMT2A
SCHEMBL16238117 0.82 PIK3CA (0.56) POLBKDM4EGAAPIK3CAPIK3CD
SCHEMBL229286 0.79 LMNA (0.57) POLBKDM4EGAAPIK3CAPIK3CD
SCHEMBL3195427 0.78 SORD (0.43) POLBKDM4EMAPK1SMN1; SMN2KMT2A
SCHEMBL9803609 0.78 SORD (0.43) POLBKDM4EGAAMAPK1SMN1; SMN2
Hydrochloric Acid SCHEMBL7714167 0.77 KDM4E (0.57) POLBKDM4EGAAPIK3CAPIK3CD
SCHEMBL2524177 0.77 MAPK1 (0.58) KDM4EGAAPIK3CAPIK3CDPIK3CB
SCHEMBL3197967 0.76 SORD (0.42) POLBKDM4ESMN1; SMN2KMT2ALMNA
SCHEMBL3198845 0.76 SORD (0.42) POLBKDM4ESMN1; SMN2KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3194482-B1 USE OF PHOSPHOROUS-CONTAINING ORGANIC OXYIMIDES AS FLAME RETARDANTS FOR PLASTICS, FLAME-RETARDANT PLASTIC COMPOSITIONS, METHOD FOR THE PRODUCTION THEREOF, MOULDED PART, PAINT AND COATINGS FRAUNHOFER GES FORSCHUNG (DE) 2024-05-08 EP claimed
CN-111251493-B Granulation method of hindered amine light stabilizer 天津利安隆新材料股份有限公司 2022-05-31 CN claimed
CN-110343205-A Side group functionalized polyisobutylene base thermoplastic elastomer and preparation method thereof 北京化工大学 2019-10-18 CN claimed
CN-108191837-A PI3K α/mTOR bidifly enzyme inhibitors and its pharmaceutical composition and application 贵州医科大学 2018-06-22 CN claimed
CN-106206795-B A kind of high water resistant back veneer material easy to clean for big system photovoltaic module 杭州福斯特应用材料股份有限公司 2017-09-29 CN claimed
CN-104494263-B A kind of high office electric discharge pressure photovoltaic back 杭州福斯特光伏材料股份有限公司 2016-08-24 CN claimed
CN-101765629-A Halogen-free flame retardants BUDENHEIM KG CHEM FAB 2010-06-30 CN claimed
US-12553011-B2 Solid free-flowing particulate laundry detergent composition THE PROCTER & GAMBLE COMPANY (US) 2026-02-17 US disclosed
CN-119410585-A Gastrointestinal stromal tumor organoid culture solution and use method and application thereof 福建瑞庚生物科技有限公司 2025-02-11 CN disclosed
US-11987718-B2 Coating composition for producing a layer composite MITSUBISHI HITEC PAPER EUROPE GMBH (DE) 2024-05-21 US disclosed
US-11986482-B2 Method of promoting antitumor or anti-cancer immunity CITY UNIVERSITY OF HONG KONG (HK) 2024-05-21 US disclosed
US-20230416645-A1 SOLID FREE-FLOWING PARTICULATE LAUNDRY DETERGENT COMPOSITION THE PROCTER & GAMBLE COMPANY 2023-12-28 US disclosed
EP-4281447-A1 TRIAZINE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME Athos Therapeutics, Inc. (US) 2023-11-29 EP disclosed
US-6384032-B1 INTERLEUKIN INHIBITORS SHIONOGI BIORESEARCH CORP. 2002-05-07 US disclosed
EP-1185528-A1 INHIBITORS OF IL-12 PRODUCTION Shionogi Bioresearch Corporation (US) 2002-03-13 EP disclosed
WO-2000078757-A1 INHIBITORS OF IL-12 PRODUCTION SHIONOGI BIORESEARCH CORP. (US) 2000-12-28 WO disclosed
US-5455318-A Metathetical polymerization in presence of catalyst based on tungsten compound reacted with sterically hindered amine and solution of cocatalyst CHEMOPETROL, S.P. LITVINOV, VYZKUMNY USTAV MAKROMOLEKULARNI CHEMIE (CS) 1995-10-03 US disclosed
US-4370443-A QUATERNARY AMMONIUM POLYTRIAZINES, MORDANTS, FIXING AGENTS, CATIONIC SURFACTANTS STERLING DRUG INC. (US) 1983-01-25 US disclosed
US-4347352-A REACTING CYANURIC CHLORIDE WITH A TERTIARY AMINE; FOR USE AS MORDANTS, SOFTENERS, SURFACTANTS STERLING DRUG INC. (US) 1982-08-31 US disclosed
US-4314001-A FOR SOFTENING FIBERS; TRIAZINE QUATERNARY AMMONIUM POLYMERS STERLING DRUG INC. (US) 1982-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11986482-B2 Method of promoting antitumor or anti-cancer immunity PDCD1, CD274, PDCD1LG2 POLB 2925/4885KDM4E 2122/4885GAA 256/4885
US-12553011-B2 Solid free-flowing particulate laundry detergent composition SCLY, LPO, PLD1 POLB 1003/4885KDM4E 1416/4885GAA 1718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.