Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 2/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid Monomethyl Ester SCHEMBL9078007 | 0.82 | XDH (0.53) | XDHPTPN1RARARARBRARG | |
| Phosphoric Acid Monomethyl Ester SCHEMBL9440650 | 0.82 | XDH (0.53) | XDHPTPN1RARARARBRARG | |
| SCHEMBL9078396 | 0.82 | TTR (0.47) | PTPN1FBP1 | |
| SCHEMBL9075940 | 0.78 | XDH (0.51) | XDHPTPN1RARARARBRARG | |
| SCHEMBL9078702 | 0.74 | CA12 (0.34) | ALDH1A1CA1CA2POLB | |
| SCHEMBL13347435 | 0.74 | PTPN1 (0.65) | XDHPTPN1FBP1ALDH1A1CA1 | |
| SCHEMBL9075079 | 0.72 | CA12 (0.33) | CA1CA2 | |
| SCHEMBL7647202 | 0.72 | TSHR (0.52) | ALDH1A1CA1CA2MAPTTP53 | |
| Terephthalic Acid SCHEMBL28295430 | 0.72 | CA1 (0.58) | ALDH1A1CA1CA2TDP1TP53 | |
| Terephthalic Acid SCHEMBL28295429 | 0.72 | CA1 (0.58) | ALDH1A1CA1CA2TDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519953-B1 | ACYL PHOSPHATE ESTERS AND MODIFICATION OF PROTEINS THEREWITH | UNIV TORONTO (CA) | 1996-02-07 | — | — | EP | disclosed |