Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.31 |
| ▸ | TPMT | P51580 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9078702 | 0.85 | CA12 (0.34) | CA12CA1CA2CA3PKM | |
| Phosphoric Acid Monomethyl Ester SCHEMBL9424981 | 0.74 | CA1 (0.48) | CA12CA1CA2CA3PKM | |
| SCHEMBL9078010 | 0.72 | XDH (0.42) | CA1CA2 | |
| SCHEMBL9078315 | 0.72 | CA1 (0.47) | CA12CA1CA2CA3PKM | |
| SCHEMBL9078396 | 0.71 | TTR (0.47) | — | |
| SCHEMBL143011 | 0.70 | CA12 (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28578709 | 0.70 | TPMT (0.55) | CA12CA1CA2CA3PKM | |
| SCHEMBL9767572 | 0.70 | FDPS (0.45) | — | |
| SCHEMBL9767659 | 0.68 | FDPS (0.43) | — | |
| Phenol SCHEMBL28010832 | 0.66 | ESR1 (0.39) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519953-B1 | ACYL PHOSPHATE ESTERS AND MODIFICATION OF PROTEINS THEREWITH | UNIV TORONTO (CA) | 1996-02-07 | — | — | EP | claimed |
| US-5250665-A | Artificial blood | THE UNIVERSITY OF TORONTO INNOVATIONS FOUNDATION (CA) | 1993-10-05 | — | — | US | disclosed |
| WO-1992021702-A1 | SPECIFICALLY BETA-BETA CROSS-LINKED HEMOGLOBINS AND METHOD OF PREPARATION | THE UNIVERSITY OF TORONTO INNOVATIONS FOUNDATION (CA) | 1992-12-10 | — | — | WO | disclosed |