Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | CA6 | P23280 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TPMT | P51580 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075079 | 0.85 | CA12 (0.33) | CA12CA1CA2CA4CA6 | |
| Phosphoric Acid Monomethyl Ester SCHEMBL9424981 | 0.76 | CA1 (0.48) | CA12CA1CA2CA4CA6 | |
| SCHEMBL9078010 | 0.74 | XDH (0.42) | CA1CA2POLBALDH1A1 | |
| SCHEMBL9078396 | 0.73 | TTR (0.47) | — | |
| SCHEMBL28578709 | 0.72 | TPMT (0.55) | CA12CA1CA2CA4CA6 | |
| SCHEMBL9078315 | 0.70 | CA1 (0.47) | CA12CA1CA2CA4CA6 | |
| SCHEMBL10615801 | 0.70 | FDPS (0.47) | CA2ALDH1A1 | |
| SCHEMBL1758661 | 0.70 | FDPS (0.53) | CA2ALDH1A1 | |
| SCHEMBL143011 | 0.69 | CA12 (0.39) | CA12CA1CA2CA7CA9 | |
| Fluoride SCHEMBL27641642 | 0.68 | LMNA (0.44) | CA12CA1CA9KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519953-B1 | ACYL PHOSPHATE ESTERS AND MODIFICATION OF PROTEINS THEREWITH | UNIV TORONTO (CA) | 1996-02-07 | — | — | EP | claimed |