Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782246 | 1.00 | HTT (0.40) | HTTALDH1A1MAPTHPGDMAOB | |
| SCHEMBL10363296 | 0.88 | MAOB (0.42) | HTTALDH1A1MAPTHPGDMAOB | |
| SCHEMBL10370916 | 0.86 | RAB9A (0.42) | ALDH1A1MAPTHPGDMAOBRAB9A | |
| SCHEMBL7811546 | 0.84 | RAB9A (0.43) | ALDH1A1MAPTHPGDMAOBRAB9A | |
| SCHEMBL6398540 | 0.83 | TDP1 (0.43) | HTTALDH1A1MAPTHPGDMAOB | |
| SCHEMBL8759638 | 0.83 | TDP1 (0.43) | HTTALDH1A1MAPTHPGDMAOB | |
| SCHEMBL10364355 | 0.83 | TDP1 (0.43) | HTTALDH1A1MAPTHPGDMAOB | |
| SCHEMBL9519480 | 0.83 | RAB9A (0.40) | ALDH1A1MAPTHPGDRAB9ANPC1 | |
| SCHEMBL9518937 | 0.83 | ALDH1A1 (0.38) | HTTALDH1A1MAPTHPGDMAOB | |
| SCHEMBL9794979 | 0.83 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDMAOBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523415-A | BACTERICIDES | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-06-04 | — | — | US | disclosed |
| US-5360798-A | BACTERICIDES | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0521524-A1 | Aminooxypyrrolidinylthiocarbapenem compounds | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-01-07 | — | — | EP | disclosed |