Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9078175 | 0.85 | LMNA (0.38) | ALDH1A1CA9SMN1; SMN2TSHRMAPT | |
| SCHEMBL29246879 | 0.83 | CA2 (0.39) | KDM4EALDH1A1HSD17B10CA2VCAM1 | |
| SCHEMBL29246851 | 0.83 | VCAM1 (0.39) | KDM4EALDH1A1HSD17B10CA2VCAM1 | |
| SCHEMBL9075730 | 0.82 | VCAM1 (0.38) | KDM4EALDH1A1HSD17B10CA2VCAM1 | |
| SCHEMBL3437073 | 0.82 | CDK1 (0.40) | KDM4EALDH1A1HSD17B10CA2VCAM1 | |
| SCHEMBL18299405 | 0.82 | ALDH1A1 (0.40) | KDM4EALDH1A1HSD17B10CA2CA1 | |
| SCHEMBL3436911 | 0.80 | VCAM1 (0.39) | KDM4EALDH1A1HSD17B10CA2VCAM1 | |
| SCHEMBL6752534 | 0.80 | CDK1 (0.36) | KDM4EALDH1A1HSD17B10CA2VCAM1 | |
| SCHEMBL9078381 | 0.79 | ALDH1A1 (0.39) | KDM4EALDH1A1HSD17B10CA2VCAM1 | |
| SCHEMBL6607515 | 0.79 | ABL1 (0.38) | KDM4EALDH1A1HSD17B10CA2VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282944-B1 | Pyrazole derivative and herbicide containing it | NISSAN CHEMICAL IND LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5175299-A | Benzoic acid derivatives useful as intermediates for the preparation of herbicidal 4-benzoylpyrazoles | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| US-4948887-A | FOR UPLAND FIELDS | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1990-08-14 | — | — | US | disclosed |
| EP-0282944-A2 | Pyrazole derivative and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |