Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302004 | 0.87 | LMNA (0.55) | LMNANR3C2NR3C1MGLLCCR2 | |
| SCHEMBL7304686 | 0.83 | LMNA (0.48) | LMNANR3C2NR3C1MGLLSMN1; SMN2 | |
| Fumaric Acid SCHEMBL9229142 | 0.83 | LMNA (0.51) | LMNANR3C2NR3C1MGLL | |
| SCHEMBL7298261 | 0.81 | LMNA (0.58) | LMNANR3C2NR3C1MGLLSMN1; SMN2 | |
| SCHEMBL8544144 | 0.79 | LMNA (0.53) | LMNANR3C2NR3C1MGLLSMN1; SMN2 | |
| SCHEMBL7300845 | 0.79 | LMNA (0.58) | LMNANR3C2NR3C1MGLLSMN1; SMN2 | |
| SCHEMBL7301998 | 0.76 | LMNA (0.53) | LMNANR3C2NR3C1MGLL | |
| SCHEMBL7299793 | 0.76 | LMNA (0.59) | LMNANR3C2NR3C1 | |
| SCHEMBL7305217 | 0.72 | LMNA (0.72) | LMNANR3C2NR3C1 | |
| SCHEMBL7299169 | 0.71 | LMNA (0.58) | LMNANR3C2NR3C1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550125-A | BRAIN DISORDERS | SYNTHELABO (FR) | 1996-08-27 | — | — | US | disclosed |