Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 2/20 | 0.30 |
| ▸ | MC5R | P33032 | 1/20 | 0.30 |
| ▸ | MC3R | P41968 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483534 | 0.98 | LTB4R2 (0.37) | LTB4R2AGTR1PKMPTGDR2AGTR2 | |
| SCHEMBL8488532 | 0.97 | AGTR1 (0.37) | LTB4R2AGTR1PKMPTGDR2AGTR2 | |
| SCHEMBL8486859 | 0.95 | LTB4R2 (0.34) | LTB4R2AGTR1PKMPTGDR2MC4R | |
| SCHEMBL9080460 | 0.94 | LTB4R2 (0.34) | LTB4R2AGTR1PKMPTGDR2 | |
| SCHEMBL9080766 | 0.92 | OPRM1 (0.34) | LTB4R2 | |
| SCHEMBL8488672 | 0.91 | PTGDR2 (0.35) | LTB4R2AGTR1PKMPTGDR2AGTR2 | |
| SCHEMBL8806706 | 0.90 | LTB4R2 (0.34) | LTB4R2AGTR1PKMPTGDR2AGTR2 | |
| SCHEMBL8912327 | 0.90 | AGTR1 (0.41) | LTB4R2AGTR1PKMPTGDR2AGTR2 | |
| SCHEMBL8486854 | 0.88 | AGTR1 (0.37) | LTB4R2AGTR1PKMPTGDR2AGTR2 | |
| SCHEMBL8910347 | 0.88 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506240-A | HYPOTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1996-04-09 | — | — | US | disclosed |