SCHEMBL9079902

SCHEMBL9079902

c1ccc(CN(Cc2ccccc2)Oc2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.46
ALDH1A1 P00352 3/20 0.46
AOC3 Q16853 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
BCHE P06276 1/20 0.40
MAPK1 P28482 1/20 0.39
CA2 P00918 1/20 0.39
NR3C1 P04150 2/20 0.39
CYP2C19 P33261 2/20 0.38
CARM1 Q86X55 1/20 0.38
PRMT6 Q96LA8 1/20 0.38
PRMT8 Q9NR22 1/20 0.38
SLC22A2 O15244 1/20 0.38
SLC22A1 O15245 1/20 0.38
SLC22A3 O75751 1/20 0.38
ESR1 P03372 1/20 0.38
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9079845 0.98 ALDH1A1 (0.44) TSHRALDH1A1AOC3SMN1; SMN2NPC1
SCHEMBL9178257 0.87 TSHR (0.47) TSHRALDH1A1AOC3SMN1; SMN2NPC1
SCHEMBL8497182 0.82 CYP1A2 (0.49) TSHRALDH1A1SMN1; SMN2HTR1ADRD2
SCHEMBL8497082 0.82 MAPT (0.47) TSHRALDH1A1SMN1; SMN2MAPK1KMT2A
SCHEMBL7760999 0.82 TRPM8 (0.44) TSHRALDH1A1SMN1; SMN2CHRM2CHRM1
SCHEMBL28458578 0.77 TSHR (0.43) TSHRALDH1A1AOC3SMN1; SMN2NPC1
SCHEMBL12476817 0.77 TSHR (0.52) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL8498728 0.77 BCHE (0.39) TSHRALDH1A1AOC3SMN1; SMN2NPC1
SCHEMBL8496296 0.77 OPRM1 (0.44) NPC1RAB9AOPRM1OPRD1
SCHEMBL8496481 0.76 TSHR (0.44) TSHRALDH1A1AOC3SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996034851-A1 BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE ABBOTT LABORATORIES (US) 1996-11-07 WO disclosed