Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.35 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.35 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080204 | 0.76 | CYP2C9 (0.39) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL9080214 | 0.76 | CYP2C9 (0.39) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL7562901 | 0.67 | KDM4E (0.55) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL8384592 | 0.66 | KLKB1 (0.47) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL7852526 | 0.64 | CFD (0.46) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL28222381 | 0.64 | CFD (0.46) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL254346 | 0.63 | KAT8 (0.54) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL15006288 | 0.63 | XDH (0.50) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL28699073 | 0.63 | KLKB1 (0.44) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL23103 | 0.63 | LCK (0.62) | KLKB1CTSBMMP9DNMT1DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |