Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7396532 | 0.88 | ITGB3 (0.44) | HRH3HRH1HRH2ITGB3ITGA2B | |
| SCHEMBL9277628 | 0.85 | HRH3 (0.46) | HRH3FAAHHRH1HRH2ITGB3 | |
| SCHEMBL7334450 | 0.83 | HRH3 (0.57) | HRH3FAAHHRH1HRH2ITGB3 | |
| SCHEMBL8889829 | 0.80 | HRH3 (0.58) | HRH3FAAHHRH1HRH2ITGB3 | |
| SCHEMBL8603764 | 0.78 | ITGB3 (0.47) | HRH3HRH1HRH2ITGB3ITGA2B | |
| SCHEMBL8633838 | 0.75 | CHKA (0.34) | ITGB3ITGA2BMAPT | |
| SCHEMBL7333032 | 0.75 | HRH3 (0.47) | HRH3FAAHHRH1HRH2ITGB3 | |
| SCHEMBL8635810 | 0.74 | NPSR1 (0.34) | HRH3ITGB3ITGA2B | |
| SCHEMBL7400705 | 0.73 | ITGB3 (0.50) | HRH3HRH1HRH2ITGB3ITGA2B | |
| SCHEMBL7403373 | 0.73 | FAAH (0.54) | HRH3FAAHHRH1HRH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556977-A | ANTIAGGLOMERANTS FOR CELLS, ANTICOAGULANTS, ANTIISCHEMIC AGENTS USING PYRIDINYLPIPERAZINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-09-17 | — | — | US | disclosed |