SCHEMBL9080423

SCHEMBL9080423

Cc1ccc(C(C)(C)C(C)C(O)C(C)(C)C)cc1C

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.34
VDR P11473 1/20 0.33
CYP19A1 P11511 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
PDE2A O00408 1/20 0.32
KIF11 P52732 2/20 0.31
MEN1 O00255 1/20 0.30
MITF O75030 1/20 0.30
KMT2A Q03164 1/20 0.30
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TRPA1 O75762 1/20 0.30
ESR2 Q92731 1/20 0.30
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8736799 0.69 TDP1 (0.39) ESR1VDRTDP1KIF11KMT2A
SCHEMBL1713303 0.69 TDP1 (0.39) ESR1VDRTDP1KIF11KMT2A
SCHEMBL10001975 0.66 MEN1 (0.48) ESR1CYP19A1TDP1KIF11MEN1
SCHEMBL12051657 0.66 ESR1 (0.44) ESR1CYP19A1TDP1PDE2AKIF11
SCHEMBL9064553 0.65 ESR1 (0.61) ESR1CYP19A1TDP1KIF11MEN1
SCHEMBL2009857 0.65 TSHR (0.52) ESR1CYP19A1TDP1KIF11MEN1
SCHEMBL29498849 0.65 TSHR (0.52) ESR1CYP19A1TDP1KIF11MEN1
SCHEMBL10227947 0.65 ALDH1A1 (0.40) VDRTDP1KIF11ALDH1A1CNR1
SCHEMBL23639732 0.63 KIF11 (0.38) VDRTDP1KIF11
SCHEMBL6672276 0.63 KIF11 (0.40) CYP19A1TDP1KIF11KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5559272-A Aromatic compounds FIRMENICH S.A. (CH) 1996-09-24 US disclosed
US-5442124-A Process for the preparation of novel aromatic compounds FIRMENICH SA (CH) 1995-08-15 US disclosed
EP-0405427-B1 Aromatic compounds, process for their preparation and their use as perfuming ingredients FIRMENICH & CIE (CH) 1995-03-29 EP disclosed
WO-1995000114-A1 TETRALINE® FORMATE ESTER AROMA CHEMICALS UNION CAMP CORPORATION (US) 1995-01-05 WO disclosed
US-5324875-A Musk odor FIRMENICH SA (CH) 1994-06-28 US disclosed
US-5292719-A Perfumes, colognes, soaps and cosmetics; musk aroma UNION CAMP CORPORATION (US) 1994-03-08 US disclosed
US-5185318-A Aromatic compounds, a process for preparation thereof and use of same as perfuming ingredients FIRMENICH S.A. (CH) 1993-02-09 US disclosed
US-5162588-A Muky type odor; colognes, shaving lotions, soaps, bath gels, shampoos, hair care products FIRMENICH S.A. (CH) 1992-11-10 US disclosed
EP-0405427-A2 Aromatic compounds, process for their preparation and their use as perfuming ingredients FIRMENICH SA (CH) 1991-01-02 EP disclosed