Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621182 | 0.77 | GAA (0.44) | VNN1EGFRERBB2KMT2AALDH1A1 | |
| SCHEMBL8711809 | 0.77 | FFAR4 (0.45) | MAPK1VNN1MEN1KMT2ACYP1A2 | |
| SCHEMBL8983934 | 0.73 | MAPT (0.31) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL24890434 | 0.70 | L3MBTL1 (0.51) | MAPK1VNN1MEN1KMT2ACYP2C9 | |
| SCHEMBL8783743 | 0.68 | AKR1B1 (0.57) | HTR2CHTR6KMT2ACYP1A2CYP2C9 | |
| SCHEMBL8526128 | 0.67 | SLC6A4 (0.41) | MEN1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL3966352 | 0.67 | MAOA (0.46) | MEN1KMT2ATERTCYP1A2CYP2C9 | |
| SCHEMBL29572439 | 0.67 | MAOA (0.46) | MEN1KMT2ATERTCYP1A2CYP2C9 | |
| SCHEMBL10547697 | 0.66 | ENPP2 (0.42) | HTR2CHTR6MEN1KMT2AMAPT | |
| SCHEMBL9082463 | 0.66 | HTR2C (0.42) | MAPK1HTR2CHTR6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736006-A1 | PHENYLTHIOPHENYL CYCLOALKENYL HYDROXYUREAS AS LIPOXYGENASE INHIBITORS | PFIZER INC. (US) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017379-A1 | PHENYLTHIOPHENYL CYCLOALKENYL HYDROXYUREAS AS LIPOXYGENASE INHIBITORS | PFIZER INC. (US) | 1995-06-29 | — | — | WO | disclosed |