Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081519 | 0.87 | ALOX5 (0.38) | ALOX5MGLL | |
| SCHEMBL9230200 | 0.78 | MGLL (0.35) | MGLLKDM4C | |
| SCHEMBL607599 | 0.76 | SLC9A1 (0.30) | — | |
| SCHEMBL8707063 | 0.72 | ALOX5 (0.44) | ALOX5 | |
| SCHEMBL8778130 | 0.71 | ALOX5 (0.65) | ALOX5MGLL | |
| SCHEMBL8778127 | 0.71 | ALOX5 (0.65) | ALOX5MGLL | |
| SCHEMBL9226766 | 0.71 | MGLL (0.34) | MGLL | |
| Hydroxyurea SCHEMBL8712235 | 0.69 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL8706620 | 0.69 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9081715 | 0.68 | L3MBTL1 (0.39) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736006-A1 | PHENYLTHIOPHENYL CYCLOALKENYL HYDROXYUREAS AS LIPOXYGENASE INHIBITORS | PFIZER INC. (US) | 1996-10-09 | — | — | EP | claimed |
| WO-1995017379-A1 | PHENYLTHIOPHENYL CYCLOALKENYL HYDROXYUREAS AS LIPOXYGENASE INHIBITORS | PFIZER INC. (US) | 1995-06-29 | — | — | WO | claimed |
| EP-0736006-A1 | PHENYLTHIOPHENYL CYCLOALKENYL HYDROXYUREAS AS LIPOXYGENASE INHIBITORS | PFIZER INC. (US) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017379-A1 | PHENYLTHIOPHENYL CYCLOALKENYL HYDROXYUREAS AS LIPOXYGENASE INHIBITORS | PFIZER INC. (US) | 1995-06-29 | — | — | WO | disclosed |