Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012498 | 0.87 | HTR1A (0.44) | KMT2AMEN1ALDH1A1HPGDHTR1A | |
| SCHEMBL8345231 | 0.84 | KDM4E (0.45) | KMT2AMEN1KDM4EGAAALDH1A1 | |
| SCHEMBL7011022 | 0.83 | KDM4E (0.44) | KMT2AMEN1KDM4EGAAALDH1A1 | |
| SCHEMBL23888978 | 0.78 | GAA (0.44) | KMT2AMEN1KDM4EGAAALDH1A1 | |
| SCHEMBL8327321 | 0.77 | PLA2G1B (0.43) | KMT2AMEN1ALDH1A1HTR1ASLC6A2 | |
| SCHEMBL19127912 | 0.76 | KDM4E (0.43) | KMT2AMEN1KDM4EGAAALDH1A1 | |
| SCHEMBL3952696 | 0.76 | RXRA (0.49) | MAPT | |
| SCHEMBL13794527 | 0.75 | MAPT (0.45) | GAAALDH1A1HPGDPPIAMAPT | |
| SCHEMBL7011352 | 0.74 | FOLH1 (0.47) | ALDH1A1MAPT | |
| SCHEMBL27477173 | 0.74 | HTR1A (0.43) | KMT2AMEN1KDM4EALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996003383-A1 | INDOLIZINE sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |