Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9079780 | 0.92 | KDM4E (0.67) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL9080159 | 0.84 | ALDH1A1 (0.61) | ALDH1A1POLBKDM4ECYP1A2CYP3A4 | |
| SCHEMBL19140453 | 0.83 | ALDH1A1 (0.55) | ALDH1A1POLBKDM4ECYP1A2CYP3A4 | |
| SCHEMBL8037895 | 0.79 | ALDH1A1 (0.64) | ALDH1A1POLBKDM4EKMT2AHSD17B10 | |
| SCHEMBL9081539 | 0.79 | SMN1; SMN2 (0.56) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL6340707 | 0.78 | KMT2A (0.61) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL8041179 | 0.77 | ALDH1A1 (0.52) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL6349020 | 0.77 | ALDH1A1 (0.60) | ALDH1A1POLBKDM4EKMT2AHSD17B10 | |
| SCHEMBL22022912 | 0.77 | ALDH1A1 (0.57) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL8041208 | 0.76 | FFAR1 (0.48) | ALDH1A1POLBKDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |