Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | PLOD2 | O00469 | 3/20 | 0.48 |
| ▸ | PLOD3 | O60568 | 3/20 | 0.48 |
| ▸ | PLOD1 | Q02809 | 3/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341384 | 0.98 | ALDH1A1 (0.66) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL340946 | 0.85 | KMO (0.68) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL10739904 | 0.85 | PLOD2 (0.66) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL5356965 | 0.84 | ALDH1A1 (0.64) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL1397690 | 0.83 | GAA (0.72) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL30290422 | 0.83 | GAA (0.72) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL10691285 | 0.83 | ALDH1A1 (0.62) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL10755573 | 0.83 | ALDH1A1 (0.66) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL4630423 | 0.82 | GAA (0.70) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL1397363 | 0.82 | GAA (0.74) | ALDH1A1HPGDMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010563-A1 | 2-ARYL-4-QUINOLONES AS ANTITUMOR COMPOUNDS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-04-11 | — | — | WO | disclosed |