Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | PLOD2 | O00469 | 3/20 | 0.51 |
| ▸ | PLOD3 | O60568 | 3/20 | 0.51 |
| ▸ | PLOD1 | Q02809 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10691285 | 0.98 | ALDH1A1 (0.62) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL10755573 | 0.98 | ALDH1A1 (0.66) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL7351790 | 0.85 | PLOD2 (0.52) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL3831932 | 0.85 | KMO (0.68) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL9081605 | 0.84 | ALDH1A1 (0.64) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL341384 | 0.83 | ALDH1A1 (0.66) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL32688300 | 0.82 | ALDH1A1 (0.54) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL8349198 | 0.82 | ALDH1A1 (0.70) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL17928976 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL10144997 | 0.81 | ALOX5 (0.60) | ALDH1A1HPGDMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307091-B2 | Deuterated 3-piperidinopropiophenone and medicaments containing said compounds | BDD BEROLINA DRUG DEVELOPMENT GMBH (DE) | 2007-12-11 | — | — | US | claimed |
| CN-101002770-A | Deuterated 3-piperidinophenylethyl ketones and pharmaceutical compositions containing them | BDD BEROLINA DRUG DEV GMBH (DE) | 2007-07-25 | — | — | CN | claimed |
| CN-1293064-C | Deuterated 3-piperidinopropiophenone and pharmaceutical compositions containing same | TOURIKOUM DRUG DEV AB (DE) | 2007-01-03 | — | — | CN | claimed |
| EP-1383752-B1 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | TURICUM DRUG DEV AG (CH) | 2005-06-22 | — | — | EP | claimed |
| US-20040186136-A1 | Deuterated 3-piperidinopropiophenone and medicaments containing said compounds | BDD BEROLINA DRUG DEVELOPMENT GMBH (DE) | 2004-09-23 | — | — | US | claimed |
| CN-1527823-A | Deuterated 3-piperidinopropiophenone and pharmaceutical compositions containing same | ͼ���ķҩ�x{FDE2}չ�ɷݹ�˾ | 2004-09-08 | — | — | CN | claimed |
| EP-1383752-A2 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | Turicum Drug Development AG (CH) | 2004-01-28 | — | — | EP | claimed |
| WO-2002088100-A2 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | TURICUM DRUG DEVELOPMENT AG (CH) | 2002-11-07 | — | — | WO | claimed |
| CN-105164125-A | 2-phenyl or 2-heteroaryl imidazo [1, 2-a ] pyridine derivatives | HOFFMANN LA ROCHE | 2015-12-16 | — | — | CN | disclosed |
| CN-101311171-B | Compound with dual restraining activities to acetyl cholinesterase and butyryl cholinesterase and use thereof | INST MATERIA MEDICA CAMS | 2011-09-28 | — | — | CN | disclosed |
| CN-101311171-A | Compound with dual restraining activities to acetyl cholinesterase and butyryl cholinesterase and use thereof | INST MATERIA MEDICA CAMS (CN) | 2008-11-26 | — | — | CN | disclosed |
| US-7307091-B2 | Deuterated 3-piperidinopropiophenone and medicaments containing said compounds | BDD BEROLINA DRUG DEVELOPMENT GMBH (DE) | 2007-12-11 | — | — | US | disclosed |
| US-7307091-B2 | Deuterated 3-piperidinopropiophenone and medicaments containing said compounds | BDD BEROLINA DRUG DEVELOPMENT GMBH (DE) | 2007-12-11 | — | — | US | disclosed |
| US-7307091-B2 | Deuterated 3-piperidinopropiophenone and medicaments containing said compounds | BDD BEROLINA DRUG DEVELOPMENT GMBH (DE) | 2007-12-11 | — | — | US | disclosed |
| CN-1527823-A | Deuterated 3-piperidinopropiophenone and pharmaceutical compositions containing same | ͼ���ķҩ�x{FDE2}չ�ɷݹ�˾ | 2004-09-08 | — | — | CN | disclosed |
| EP-1383752-A2 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | Turicum Drug Development AG (CH) | 2004-01-28 | — | — | EP | disclosed |
| EP-1383752-A2 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | Turicum Drug Development AG (CH) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002088100-A3 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | BEROLINA DRUG DEV AB (SE) | 2003-05-30 | — | — | WO | disclosed |
| WO-2002088100-A2 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | TURICUM DRUG DEVELOPMENT AG (CH) | 2002-11-07 | — | — | WO | disclosed |
| WO-2002088100-A2 | DEUTERATED 3-PIPERIDINOPROPIOPHENONE AND MEDICAMENTS CONTAINING SAID COMPOUNDS | TURICUM DRUG DEVELOPMENT AG (CH) | 2002-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186136-A1 | Deuterated 3-piperidinopropiophenone and medicaments containing said compounds | MUSK, CPT1B, PYGM | ALDH1A1 1601/4885HPGD 223/4885MEN1 3056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.