Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | HCK | P08631 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9083000 | 0.90 | ALDH1A1 (0.39) | CYP3A4ALOX15HSD17B10MAP4K1KDM4E | |
| SCHEMBL9023407 | 0.86 | TDP1 (0.41) | CYP3A4ALOX15HSD17B10MAP4K1KDM4E | |
| SCHEMBL14029047 | 0.81 | NISCH (0.41) | NISCH | |
| SCHEMBL9023749 | 0.77 | MAPT (0.53) | CYP3A4ALOX15MEN1POLBGAA | |
| SCHEMBL9082242 | 0.76 | ALDH1A1 (0.43) | ALOX15HSD17B10KDM4EMEN1POLB | |
| SCHEMBL9082170 | 0.75 | NISCH (0.53) | CYP3A4ALOX15HSD17B10NISCH | |
| SCHEMBL14854498 | 0.70 | PRMT1 (0.45) | KDM4EMAPTRAB9A | |
| SCHEMBL24312945 | 0.70 | ALOX5 (0.47) | HSD17B10KDM4EMEN1GAAMAPT | |
| SCHEMBL9112216 | 0.68 | NPC1 (0.33) | POLBGAAMAPTRAB9AEGFR | |
| SCHEMBL2237656 | 0.68 | ADRB2 (0.41) | CYP3A4KDM4EGAAMAPTNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996028443-A1 | THERAPEUTIC BENZOXAZOLES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-09-19 | — | — | WO | disclosed |