Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9082178 | 0.90 | CYP3A4 (0.46) | GAAALOX15HSD17B10MEN1MAPT | |
| SCHEMBL9023407 | 0.88 | TDP1 (0.41) | ALDH1A1GAAALOX15HSD17B10MEN1 | |
| SCHEMBL14029047 | 0.79 | NISCH (0.41) | LMNARECQLNISCH | |
| SCHEMBL9082242 | 0.78 | ALDH1A1 (0.43) | ALDH1A1ALOX15HSD17B10MEN1MAPT | |
| SCHEMBL9023749 | 0.76 | MAPT (0.53) | ALDH1A1GAAALOX15MEN1MAPT | |
| SCHEMBL1142890 | 0.74 | NISCH (0.53) | LMNARECQLNISCH | |
| SCHEMBL14854498 | 0.69 | PRMT1 (0.45) | MAPTKDM4E | |
| SCHEMBL24312945 | 0.67 | ALOX5 (0.47) | ALDH1A1GAAHSD17B10MEN1MAPT | |
| SCHEMBL9112216 | 0.67 | NPC1 (0.33) | GAAMAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL2237656 | 0.67 | ADRB2 (0.41) | ALDH1A1GAAMAPTKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996028443-A1 | THERAPEUTIC BENZOXAZOLES | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-09-19 | — | — | WO | disclosed |