Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | PTGES | O14684 | 2/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 7/20 | 0.51 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | FABP1 | P07148 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081725 | 0.89 | ALDH1A1 (0.59) | ALDH1A1NPSR1PTGESLPAR1LPAR5 | |
| SCHEMBL9081270 | 0.84 | LPAR1 (0.63) | PTGESLPAR1LPAR5SRD5A2 | |
| SCHEMBL9081384 | 0.82 | ALDH1A1 (0.56) | ALDH1A1NPSR1PTGESLTA4HNR1H4 | |
| SCHEMBL9080942 | 0.82 | PTGES (0.56) | PTGESLPAR1LPAR5SRD5A2 | |
| SCHEMBL9081978 | 0.81 | LPAR1 (0.53) | PTGESLPAR1LPAR5 | |
| SCHEMBL9080556 | 0.81 | SERPINE1 (0.53) | ALDH1A1NPSR1PTGESLPAR1LPAR5 | |
| SCHEMBL9080504 | 0.81 | LPAR1 (0.50) | ALDH1A1NPSR1PTGESLPAR1LPAR5 | |
| SCHEMBL9081621 | 0.80 | ALDH1A1 (0.52) | ALDH1A1NPSR1PTGESLPAR1LPAR5 | |
| SCHEMBL9081391 | 0.79 | LPAR1 (0.53) | PTGESLPAR1LPAR5 | |
| SCHEMBL9082353 | 0.79 | LPAR1 (0.59) | LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |