Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.79 |
| ▸ | TAS2R14 | Q9NYV8 | 16/20 | 0.62 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.62 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9082262 | 0.92 | PTGES (0.68) | PTGESTAS2R14CXCR3TAS2R8MEN1 | |
| SCHEMBL9081179 | 0.81 | PTGES (0.59) | PTGES | |
| SCHEMBL11821964 | 0.80 | TAS2R14 (0.65) | PTGESTAS2R14CXCR3TAS2R8MEN1 | |
| SCHEMBL11816296 | 0.80 | TAS2R14 (0.65) | PTGESTAS2R14CXCR3TAS2R8MEN1 | |
| SCHEMBL9080942 | 0.79 | PTGES (0.56) | PTGES | |
| SCHEMBL9081270 | 0.79 | LPAR1 (0.63) | PTGES | |
| SCHEMBL1278788 | 0.78 | TAS2R14 (0.97) | PTGESTAS2R14CXCR3TAS2R8MEN1 | |
| SCHEMBL1169926 | 0.77 | TAS2R14 (1.00) | PTGESTAS2R14CXCR3TAS2R8MEN1 | |
| SCHEMBL1278846 | 0.77 | TAS2R14 (1.00) | PTGESTAS2R14CXCR3TAS2R8MEN1 | |
| SCHEMBL1278616 | 0.76 | TAS2R14 (1.00) | PTGESTAS2R14CXCR3TAS2R8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996034851-A1 | BENZENE, PYRIDINE, NAPHTALENE OR BENZOPHENONE DERIVATIVES AS INHIBITORS OF SQUALENE SYNTHETASE AND PROTEIN FARNESYLTRANSFERASE | ABBOTT LABORATORIES (US) | 1996-11-07 | — | — | WO | disclosed |