SCHEMBL9083175

SCHEMBL9083175

O=C(O)c1c(Cl)c2ccccc2n1C1CCCCO1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 4/20 0.44
KDM4E B2RXH2 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
PDE10A Q9Y233 1/20 0.36
PER2 O15055 1/20 0.35
CRY1 Q16526 1/20 0.35
CRY2 Q49AN0 1/20 0.35
EP300 Q09472 1/20 0.35
CREBBP Q92793 1/20 0.35
ALDH1A1 P00352 5/20 0.34
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
LMNA P02545 2/20 0.34
USP2 O75604 1/20 0.34
POLB P06746 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5026596 0.78 CYP1A2 (0.41) KDM4EPDE10APER2CRY1CRY2
SCHEMBL25233771 0.72 MEN1 (0.40) KDM4ESMN1; SMN2RXRARXRBRXRG
SCHEMBL7901361 0.72 DAO (0.47) CCR2RXRARXRBRXRGPDE10A
SCHEMBL5026506 0.71 POLB (0.37) SMN1; SMN2PDE10APER2CRY1CRY2
Hydrochloric Acid SCHEMBL9083179 0.71 DAO (0.46) CCR2RXRARXRBRXRGPDE10A
SCHEMBL11969974 0.70 POLB (0.36) KDM4ERXRARXRBRXRGPDE10A
SCHEMBL1114562 0.69 DGAT2 (0.38) KDM4ERXRARXRBRXRGPDE10A
SCHEMBL5875217 0.69 KDM4E (0.40) KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL6070776 0.69 TP53 (0.50) KDM4EPDE10ACREBBPALDH1A1MEN1
SCHEMBL9083172 0.68 RXRA (0.39) CCR2KDM4ESMN1; SMN2RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5534530-A CHOLECYSTOKININ AGONIST OR ANTAGONIST ELF SANOFI (FR) 1996-07-09 US disclosed