Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9086781 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPTMAPK1LMNAPOLB | |
| SCHEMBL9087027 | 0.82 | ALDH1A1 (0.60) | ALDH1A1MAPTMAPK1LMNAPOLB | |
| SCHEMBL23301285 | 0.82 | PDGFRB (0.45) | ALDH1A1MAPTMAPK1LMNAPOLB | |
| SCHEMBL13467989 | 0.82 | PDGFRB (0.45) | ALDH1A1MAPTMAPK1LMNAPOLB | |
| SCHEMBL30543368 | 0.82 | PDGFRB (0.45) | ALDH1A1MAPTMAPK1LMNAPOLB | |
| SCHEMBL13851053 | 0.81 | LMNA (0.50) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| SCHEMBL9087431 | 0.80 | PKM (0.46) | ALDH1A1MAPTMAPK1LMNAPOLB | |
| SCHEMBL9089876 | 0.78 | LMNA (0.40) | ALDH1A1MAPTMAPK1LMNAPOLB | |
| SCHEMBL23301412 | 0.78 | PDGFRB (0.41) | ALDH1A1MAPTMAPK1MEN1KMT2A | |
| SCHEMBL23925436 | 0.77 | MEN1 (0.52) | ALDH1A1MAPTMAPK1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523311-A | CARBONYLOXY OR THIOCARBONYL-BENZO-1,2,3-THIADIAZOLE DERIVATIVES USED AS CHEMICAL ACTIVATOR TO STIMULATE PLANTS CAPACITY TO DEFEND ITSELF AGAINST MICROBIAL INFECTIONS | CIBA-GEIGY CORPORATION (US) | 1996-06-04 | — | — | US | disclosed |
| US-5190928-A | Benzo-1,2,3-thiadiazoles | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| US-4931581-A | CHEMICAL INTERMEDIATES FOR 1,2,3-BENZOTHIADIAZOLE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |