Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30578616 | 0.82 | SMN1; SMN2 (0.46) | ADORA3ALDH1A1CYP19A1PKMNPSR1 | |
| SCHEMBL6775691 | 0.79 | GAA (0.44) | ALDH1A1CYP19A1PKMNPSR1LMNA | |
| SCHEMBL326566 | 0.79 | ALDH1A1 (0.46) | ALDH1A1PKMNPSR1PARP1HTT | |
| SCHEMBL27600423 | 0.78 | LMNA (0.44) | ADORA3ALDH1A1CYP19A1NPSR1HTT | |
| SCHEMBL9087633 | 0.77 | EGFR (0.50) | ALDH1A1NPSR1HTTLMNANPC1 | |
| SCHEMBL18131176 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HTTLMNANPC1RAB9A | |
| SCHEMBL25251690 | 0.75 | NOS1 (0.57) | ADORA2AADORA3ADORA1ALDH1A1CYP19A1 | |
| SCHEMBL11540231 | 0.75 | ALDH1A1 (0.44) | ADORA2AADORA3ADORA1ALDH1A1CYP19A1 | |
| SCHEMBL1873627 | 0.75 | SMN1; SMN2 (0.47) | ALDH1A1PKMNPSR1HTTLMNA | |
| SCHEMBL8756843 | 0.75 | ADORA2A (0.53) | ADORA2AADORA3ADORA1ALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534267-A | Composition for the oxidative dyeing of hair containing 4,5-diaminopyrazole derivatives as well as new 4,5-diaminopyrazole derivatives and process for their synthesis | WELLA AKTIENGESELLSCHAFT (DE) | 1996-07-09 | — | — | US | disclosed |
| EP-0375977-B1 | Oxidation hairdyeing composition based upon diaminopyrazole derivatives, and these diaminopyrazole derivatives | WELLA AG (DE) | 1994-02-02 | — | — | EP | disclosed |
| US-5061289-A | AS DEVELOPERS | WELLA AKTIENGESELLSCHAFT (DE) | 1991-10-29 | — | — | US | disclosed |
| WO-1990007504-A1 | OXIDATION HAIR-DYEING AGENT CONTAINING DIAMINOPYRAZOLE DERIVATIVES AND NOVEL DIAMINOPYRAZOLE DERIVATIVES | WELLA AKTIENGESELLSCHAFT (DE) | 1990-07-12 | — | — | WO | disclosed |
| EP-0375977-A1 | Oxidation hairdyeing composition based upon diaminopyrazole derivatives, and these diaminopyrazole derivatives | Wella Aktiengesellschaft (DE) | 1990-07-04 | — | — | EP | disclosed |