Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | DCTPP1 | Q9H773 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9353161 | 0.87 | RAB9A (0.49) | RAB9ANPC1MAPTSMN1; SMN2DCTPP1 | |
| SCHEMBL9088528 | 0.85 | MAPT (0.47) | MAPTSMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL9089433 | 0.85 | RAB9A (0.47) | RAB9ANPC1MAPTSMN1; SMN2DCTPP1 | |
| SCHEMBL8644976 | 0.85 | LMNA (0.47) | RAB9ANPC1MAPTSMN1; SMN2DCTPP1 | |
| SCHEMBL8643040 | 0.83 | LMNA (0.44) | RAB9ANPC1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9090429 | 0.82 | RAB9A (0.45) | RAB9ANPC1MAPTSMN1; SMN2DCTPP1 | |
| SCHEMBL1076717 | 0.82 | MAPT (0.48) | MAPTSMN1; SMN2DCTPP1MAPK1ALDH1A1 | |
| SCHEMBL9089099 | 0.81 | SMN1; SMN2 (0.43) | RAB9ANPC1MAPTSMN1; SMN2DCTPP1 | |
| SCHEMBL9088185 | 0.80 | EGFR (0.50) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6758808 | 0.78 | MGLL (0.39) | MAPTSMN1; SMN2KDM4ELMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534267-A | Composition for the oxidative dyeing of hair containing 4,5-diaminopyrazole derivatives as well as new 4,5-diaminopyrazole derivatives and process for their synthesis | WELLA AKTIENGESELLSCHAFT (DE) | 1996-07-09 | — | — | US | disclosed |
| EP-0618903-A1 | OXIDATION HAIR DYE CONTAINING 4,5-DIAMINOPYRAZOLE DERIVATIVES AND NOVEL 4,5-DIAMINOPYRAZOLE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | Wella Aktiengesellschaft (DE) | 1994-10-12 | — | — | EP | disclosed |
| WO-1994008970-A1 | OXIDATION HAIR DYE CONTAINING 4,5-DIAMINOPYRAZOLE DERIVATIVES AND NOVEL 4,5-DIAMINOPYRAZOLE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | WELLA AKTIENGESELLSCHAFT (DE) | 1994-04-28 | — | — | WO | disclosed |