Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA7 | P43166 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 5/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9088391 | 0.87 | ADRA1A (0.41) | NPC1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL9085909 | 0.85 | ALDH1A1 (0.43) | NPC1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL9366176 | 0.83 | ALDH1A1 (0.38) | NPC1KMT2ARAB9AALDH1A1HPGD | |
| SCHEMBL9365793 | 0.81 | MAPT (0.37) | MEN1KMT2AMAPTTP53ALDH1A1 | |
| SCHEMBL8051642 | 0.81 | MAPT (0.45) | NPC1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL6964915 | 0.80 | MAPT (0.35) | NPC1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL9087618 | 0.79 | MAPT (0.35) | NPC1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL9087862 | 0.79 | TSHR (0.53) | MEN1KMT2ARAB9ACA12CA1 | |
| SCHEMBL7183586 | 0.79 | MAPT (0.37) | NPC1RAB9AMAPTSMN1; SMN2TP53 | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL8588144 | 0.78 | MAPT (0.45) | NPC1MEN1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190928-A | Benzo-1,2,3-thiadiazoles | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | claimed |
| EP-0313512-B1 | BENZOTHIADIAZOLES AND THEIR USE IN PROCESSES AND COMPOSITIONS AGAINST PLANT DISEASES | CIBA-GEIGY AG (CH) | 1992-11-25 | — | — | EP | claimed |
| EP-0313512-A2 | Benzothiadiazoles and their use in processes and compositions against plant diseases | CIBA-GEIGY AG (CH) | 1989-04-26 | — | — | EP | claimed |
| US-5523311-A | CARBONYLOXY OR THIOCARBONYL-BENZO-1,2,3-THIADIAZOLE DERIVATIVES USED AS CHEMICAL ACTIVATOR TO STIMULATE PLANTS CAPACITY TO DEFEND ITSELF AGAINST MICROBIAL INFECTIONS | CIBA-GEIGY CORPORATION (US) | 1996-06-04 | — | — | US | disclosed |
| US-5190928-A | Benzo-1,2,3-thiadiazoles | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| EP-0313512-B1 | BENZOTHIADIAZOLES AND THEIR USE IN PROCESSES AND COMPOSITIONS AGAINST PLANT DISEASES | CIBA-GEIGY AG (CH) | 1992-11-25 | — | — | EP | disclosed |
| US-4931581-A | CHEMICAL INTERMEDIATES FOR 1,2,3-BENZOTHIADIAZOLE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0313512-A2 | Benzothiadiazoles and their use in processes and compositions against plant diseases | CIBA-GEIGY AG (CH) | 1989-04-26 | — | — | EP | disclosed |