Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ILK | Q13418 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL543646 | 0.94 | MAPT (0.49) | MAPTLMNAILKKDM4EKMT2A | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL2455715 | 0.88 | ALDH1A1 (0.44) | MAPTLMNAKDM4EKMT2ATSHR | |
| SCHEMBL8530686 | 0.83 | ALDH1A1 (0.50) | MAPTLMNAILKKDM4EKMT2A | |
| SCHEMBL6964915 | 0.79 | MAPT (0.35) | MAPTLMNAILKKMT2AALDH1A1 | |
| SCHEMBL9087618 | 0.78 | MAPT (0.35) | MAPTLMNAKDM4EKMT2AGAA | |
| SCHEMBL9089945 | 0.78 | NPC1 (0.44) | MAPTLMNAKDM4EKMT2AALDH1A1 | |
| SCHEMBL9087862 | 0.78 | TSHR (0.53) | MAPTILKKDM4EKMT2AGAA | |
| SCHEMBL7183586 | 0.78 | MAPT (0.37) | MAPTLMNAILKGAAALDH1A1 | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL7986261 | 0.78 | KMT2A (0.36) | MAPTLMNAKDM4EKMT2AGAA | |
| SCHEMBL674067 | 0.77 | RAB9A (0.36) | MAPTLMNAKDM4EKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5777200-A | Chemically regulatable and anti-pathogenic DNA sequences and uses thereof | NOVARTIS FINANCE CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5767369-A | PLANT RESISTANCE | NOVARTIS FINANCE CORPORATION (US) | 1998-06-16 | — | — | US | disclosed |
| US-5654414-A | GENETIC ENGINEERING | NOVARTIS FINANCE CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |