Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16477808 | 0.92 | KCNH2 (0.43) | KCNH2P2RY12KDM1APOLBKDM4E | |
| SCHEMBL16477795 | 0.91 | KCNH2 (0.41) | KCNH2P2RY12KDM1APOLBKDM4E | |
| SCHEMBL70658 | 0.87 | DRD2 (0.44) | KCNH2P2RY12KDM1APOLBALDH1A1 | |
| SCHEMBL10088452 | 0.83 | ALDH1A3 (0.45) | KCNH2P2RY12KDM1AKDM4EALDH1A1 | |
| SCHEMBL20630878 | 0.82 | P2RY12 (0.49) | KCNH2P2RY12KDM1APOLBKDM4E | |
| SCHEMBL23118210 | 0.76 | KCNH2 (0.45) | KCNH2P2RY12KDM1AKDM4EALDH1A1 | |
| SCHEMBL12571681 | 0.76 | SCN9A (0.40) | KCNH2P2RY12KDM1AL3MBTL1PRKDC | |
| SCHEMBL13433979 | 0.75 | KDM4E (0.47) | KCNH2P2RY12KDM1APOLBKDM4E | |
| SCHEMBL12628492 | 0.75 | KCNH2 (0.36) | KCNH2P2RY12KDM1AKDM4EALDH1A1 | |
| SCHEMBL12527305 | 0.74 | GAA (0.52) | KCNH2P2RY12KDM1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129365-B2 | Water-soluble, fluorescent compounds for detection of potassium ions | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-03-06 | — | — | US | disclosed |