Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 11/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL90902 | 0.92 | KCNH2 (0.42) | KCNH2P2RY12HTR1ASLC6A4KDM1A | |
| SCHEMBL16477795 | 0.89 | KCNH2 (0.41) | KCNH2P2RY12HTR1ASLC6A4KDM1A | |
| SCHEMBL70658 | 0.85 | DRD2 (0.44) | KCNH2P2RY12HTR1ASLC6A4KDM1A | |
| SCHEMBL10088452 | 0.82 | ALDH1A3 (0.45) | KCNH2P2RY12KDM1AMEN1KMT2A | |
| SCHEMBL20630878 | 0.81 | P2RY12 (0.49) | KCNH2P2RY12KDM1AMEN1ALOX15 | |
| SCHEMBL16480262 | 0.78 | HDAC6 (0.42) | KCNH2HTR1AMEN1KMT2APOLB | |
| SCHEMBL12527305 | 0.75 | GAA (0.52) | KCNH2P2RY12KDM1AMEN1KMT2A | |
| SCHEMBL23118210 | 0.75 | KCNH2 (0.45) | KCNH2P2RY12KDM1AALOX15KMT2A | |
| SCHEMBL12571681 | 0.75 | SCN9A (0.40) | KCNH2P2RY12KDM1AL3MBTL1 | |
| SCHEMBL13433979 | 0.74 | KDM4E (0.47) | KCNH2P2RY12HTR1AKDM1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181375-B2 | Fluorescent potassium ion sensors | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-11-10 | — | — | US | disclosed |
| US-9181375-B2 | Fluorescent potassium ion sensors | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2015-11-10 | — | — | US | disclosed |
| US-20140200319-A1 | FLUORESCENT POTASSIUM ION SENSORS | Arizona Board of Regents, a body corporate of the State of Arizona Acting for and on behalf of Arizo (US) | 2014-07-17 | — | — | US | disclosed |
| US-20140200319-A1 | FLUORESCENT POTASSIUM ION SENSORS | Arizona Board of Regents, a body corporate of the State of Arizona Acting for and on behalf of Arizo (US) | 2014-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200319-A1 | FLUORESCENT POTASSIUM ION SENSORS | KCNN1, KCNN2, KCNN3 | KCNH2 11/4885P2RY12 789/4885HTR1A 4759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.