Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 4/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL9090696 | 0.88 | BCAT2 (0.47) | MEN1KMT2AKDM4EL3MBTL1AGTR1 | |
| Hexane SCHEMBL9090041 | 0.88 | KMT2A (0.46) | MEN1KMT2AKDM4EL3MBTL1AGTR1 | |
| Hexane SCHEMBL9091773 | 0.85 | AGTR1 (0.46) | MEN1KMT2AKDM4EL3MBTL1AGTR1 | |
| Hexane SCHEMBL9090961 | 0.85 | AGTR1 (0.45) | MEN1KMT2AKDM4EL3MBTL1AGTR1 | |
| SCHEMBL9091010 | 0.78 | AGTR1 (0.58) | MEN1KMT2AKDM4EL3MBTL1AGTR1 | |
| SCHEMBL9091629 | 0.78 | AGTR1 (0.77) | MEN1KMT2AKDM4EL3MBTL1AGTR1 | |
| Water SCHEMBL9090481 | 0.78 | AGTR1 (0.58) | MEN1KMT2AKDM4EL3MBTL1AGTR1 | |
| Hexane SCHEMBL9089999 | 0.77 | SORT1 (0.47) | AGTR1AGTR2PLK1PLK3 | |
| Water SCHEMBL9091581 | 0.77 | AGTR1 (0.59) | MEN1KMT2AKDM4EL3MBTL1AGTR1 | |
| Water SCHEMBL9091597 | 0.77 | AGTR1 (0.59) | MEN1KMT2AKDM4EL3MBTL1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571925-A | HORMONES INHIBITORS FOR HYPOTENSIVE AGENTS | ELI LILLY AND COMPANY (US) | 1996-11-05 | — | — | US | disclosed |
| US-5312936-A | Hypotensive agents | ELI LILLY AND COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| US-5073566-A | Hypotensive agents | ELI LILLY AND COMPANY (US) | 1991-12-17 | — | — | US | disclosed |