Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPRF | P10586 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL9089037 | 0.89 | MAPT (0.43) | KMT2AMEN1L3MBTL1KDM4EAGTR1 | |
| Hexane SCHEMBL9371099 | 0.88 | AGTR1 (0.61) | AGTR1AGTR2MAPTRAB9ASMN1; SMN2 | |
| Hexane SCHEMBL9091640 | 0.88 | MEN1 (0.51) | KMT2AMEN1L3MBTL1KDM4EAGTR1 | |
| Hexane SCHEMBL9090189 | 0.87 | PTPN1 (0.43) | KMT2AMEN1L3MBTL1KDM4EAGTR1 | |
| Hexane SCHEMBL9089999 | 0.81 | SORT1 (0.47) | AGTR1AGTR2PLK1 | |
| Hexane SCHEMBL9091773 | 0.81 | AGTR1 (0.46) | KMT2AMEN1L3MBTL1KDM4EAGTR1 | |
| SCHEMBL9090023 | 0.79 | AGTR1 (0.64) | KMT2AMEN1L3MBTL1KDM4EAGTR1 | |
| Hexane SCHEMBL9088251 | 0.78 | RAB9A (0.39) | KMT2AMEN1KDM4EMAPTPOLB | |
| Hexane SCHEMBL9090696 | 0.77 | BCAT2 (0.47) | KMT2AMEN1L3MBTL1KDM4EAGTR1 | |
| Hexane SCHEMBL9090195 | 0.75 | PLA2G4A (0.55) | KMT2AMEN1L3MBTL1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571925-A | HORMONES INHIBITORS FOR HYPOTENSIVE AGENTS | ELI LILLY AND COMPANY (US) | 1996-11-05 | — | — | US | disclosed |
| US-5563278-A | Angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0438869-B1 | Improvements in and relating to angiotensin II antagonists | LILLY CO ELI (US) | 1994-12-14 | — | — | EP | disclosed |
| US-5073566-A | Hypotensive agents | ELI LILLY AND COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0438869-A1 | Improvements in and relating to angiotensin II antagonists | ELI LILLY AND COMPANY (US) | 1991-07-31 | — | — | EP | disclosed |