Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 5/20 | 0.58 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.58 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.45 |
| ▸ | PTGFR | P43088 | 2/20 | 0.45 |
| ▸ | PTGIR | P43119 | 2/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.45 |
| ▸ | ITGAL | P20701 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9094389 | 0.84 | NFKB1 (0.66) | PTGER3PTGER2PTGER1NFKB1CA1 | |
| SCHEMBL9297750 | 0.83 | NFKB1 (0.67) | PTGER3PTGER2PTGER1NFKB1CA1 | |
| SCHEMBL211297 | 0.79 | HDAC1 (0.65) | PTGER3PTGER2PTGER1NFKB1CA1 | |
| SCHEMBL12852987 | 0.79 | HDAC1 (0.65) | PTGER3PTGER2PTGER1NFKB1CA1 | |
| SCHEMBL29393232 | 0.79 | HDAC1 (0.65) | PTGER3PTGER2PTGER1NFKB1CA1 | |
| SCHEMBL322878 | 0.79 | HDAC1 (0.65) | PTGER3PTGER2PTGER1NFKB1CA1 | |
| SCHEMBL8641080 | 0.78 | NFKB1 (0.72) | PTGER3PTGER2PTGER1NFKB1CA1 | |
| SCHEMBL11462614 | 0.78 | HDAC1 (0.62) | PTGER3PTGER2PTGER1NFKB1CA1 | |
| Hydrochloric Acid SCHEMBL11754749 | 0.78 | HDAC1 (0.62) | PTGER3PTGER2PTGER1NFKB1CA1 | |
| SCHEMBL1124437 | 0.76 | PTGS2 (0.55) | PTGER3PTGER2PTGER1NFKB1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896399-A1 | BIPHENYL AND NAPHTHYL-PHENYL HYDROXAMIC ACID DERIVATIVES | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007000383-A1 | BIPHENYL AND NAPHTHYL-PHENYL HYDROXAMIC ACID DERIVATIVES | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-01-04 | — | — | WO | disclosed |