SCHEMBL9094448

SCHEMBL9094448

N=C=O.N=C=O.c1ccc2c3c(ccc2c1)CNC3

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
ANPEP P15144 1/20 0.39
HSD17B10 Q99714 2/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP2A6 P11509 1/20 0.35
TSHR P16473 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 2/20 0.35
CYP1A2 P05177 2/20 0.35
HPGD P15428 2/20 0.35
CYP2C19 P33261 2/20 0.35
GLA P06280 1/20 0.35
CYP2C9 P11712 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
PNMT P11086 2/20 0.35
HTT P42858 1/20 0.35
CDK5 Q00535 1/20 0.35
CDK5R1 Q15078 1/20 0.35
NCOA1 Q15788 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1938502 0.89 LMNA (0.46) LMNAANPEPHSD17B10ALDH1A1CYP2A6
SCHEMBL4305708 0.79 ANPEP (0.50) LMNAANPEPHSD17B10ALDH1A1CYP2A6
SCHEMBL2562691 0.74 PNMT (0.58) PNMT
SCHEMBL123650 0.74 CD44 (0.49) LMNAKDM4EPNMT
SCHEMBL4298702 0.72 HSD17B10 (0.46) LMNAHSD17B10ALDH1A1CYP2A6TSHR
SCHEMBL687395 0.70 ALDH1A1 (0.39) LMNAANPEPHSD17B10ALDH1A1CYP2A6
Chrysene SCHEMBL5095521 0.69 HPRT1 (0.70) LMNAHSD17B10ALDH1A1CYP2A6TSHR
SCHEMBL15467504 0.69 CYP1A2 (0.46) LMNAANPEPHSD17B10ALDH1A1CYP2A6
SCHEMBL687396 0.66 ALDH1A1 (0.38) LMNAANPEPHSD17B10ALDH1A1CYP2A6
SCHEMBL2535555 0.65 ANPEP (0.55) ANPEPHSD17B10ALDH1A1CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5559247-A Carboxylate and heat-sensitive recording material using same MITSUI TOATSU CHEMICALS, INC. (JP) 1996-09-24 US disclosed