Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | PPOX | P50336 | 1/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29753145 | 1.00 | LMNA (0.61) | LMNAMAPTTP53CHEK1L3MBTL1 | |
| SCHEMBL172370 | 0.88 | LMNA (0.58) | LMNAMAPTTP53CHEK1L3MBTL1 | |
| SCHEMBL7878578 | 0.88 | LMNA (0.73) | LMNAMAPTTP53CHEK1L3MBTL1 | |
| SCHEMBL1366565 | 0.84 | LMNA (0.58) | LMNAMAPTTP53CHEK1L3MBTL1 | |
| SCHEMBL31098212 | 0.82 | CES1 (0.45) | LMNAMAPTTP53CHEK1ALDH1A1 | |
| SCHEMBL380110 | 0.81 | ALOX5 (0.61) | LMNAMAPTTP53L3MBTL1TDP1 | |
| SCHEMBL23515013 | 0.81 | MAPT (0.51) | LMNAMAPTTP53L3MBTL1TDP1 | |
| SCHEMBL9094478 | 0.81 | MAPT (0.51) | LMNAMAPTTP53CHEK1L3MBTL1 | |
| SCHEMBL6304472 | 0.81 | MAPT (0.51) | LMNAMAPTTP53L3MBTL1TDP1 | |
| SCHEMBL1367799 | 0.81 | MAPT (0.51) | LMNAMAPTTP53L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4428132-A1 | SLACK-ACTIVATING COMPOUNDS AND THEIR MEDICAL USE | Johann-Wolfgang-Goethe-Universität Frankfurt am Main (DE) | 2024-09-11 | — | — | EP | disclosed |
| US-20230277551-A1 | ANTIBACTERIAL CHEMICAL COMPOUND, ITS MANUFACTURING METHOD AND ITS USE THEREOF | NATIONAL YANG MING CHIAO TUNG UNIVERSITY (TW) | 2023-09-07 | — | — | US | disclosed |
| EP-3891503-A2 | BROAD SPECTRUM GPCR BINDING AGENTS | Promega Corporation (US) | 2021-10-13 | — | — | EP | disclosed |
| US-20200200765-A1 | BROAD SPECTRUM GPCR BINDING AGENTS | PROMEGA CORPORATION | 2020-06-25 | — | — | US | disclosed |
| WO-2020117954-A2 | BROAD SPECTRUM GPCR BINDING AGENTS | PROMEGA CORPORATION (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2012079583-A1 | SYSTEM PROVIDING CONTROLLED DELIVERY OF GASEOUS CO FOR CARBONYLATION REACTIONS | AARHUS UNIVERSITET (DK) | 2012-06-21 | — | — | WO | disclosed |
| US-4049809-A | PSYCHOTHERAPY | AMERICAN CYANAMID COMPANY (US) | 1977-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200200765-A1 | BROAD SPECTRUM GPCR BINDING AGENTS | GPR139, GPR4, GPR3 | LMNA 4395/4885MAPT 4065/4885TP53 4681/4885 |
| US-20230277551-A1 | ANTIBACTERIAL CHEMICAL COMPOUND, ITS MANUFACTURING METHOD AND ITS USE THEREOF | VIP, MRPL21, GSDMD | LMNA 4248/4885MAPT 3058/4885TP53 4618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.