Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | FER | P16591 | 1/20 | 0.55 |
| ▸ | LTK | P29376 | 1/20 | 0.55 |
| ▸ | CDK8 | P49336 | 1/20 | 0.55 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.55 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9853252 | 0.81 | MAPT (0.45) | ALOX5MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL3835155 | 0.81 | MAPT (0.48) | ALOX5MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL172370 | 0.81 | LMNA (0.58) | ALOX5MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL23600949 | 0.81 | MAPT (0.70) | ALOX5MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL3409888 | 0.81 | AHR (0.49) | ALOX5MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL23515013 | 0.81 | MAPT (0.51) | ALOX5MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL9270079 | 0.81 | CSNK1G1 (0.56) | ALOX5MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL13098107 | 0.81 | MAPT (0.62) | ALOX5MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL9967368 | 0.81 | LMNA (0.61) | ALOX5MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL6304472 | 0.81 | MAPT (0.51) | ALOX5MAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140045850-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2014-02-13 | — | — | US | claimed |
| EP-1021190-B1 | Amid derivatives as growth hormone release promotors | KAKEN PHARMA CO LTD (JP) | 2006-11-08 | — | — | EP | claimed |
| CN-119285628-A | Compounds for the treatment and prophylaxis of respiratory syncytial virus infection diseases | 石药集团中奇制药技术（石家庄）有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| EP-3555095-B1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-04-12 | — | — | EP | disclosed |
| WO-2022133551-A1 | HISTONE DEACETYLASE INHIBITORS | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-06-30 | — | — | WO | disclosed |
| US-11046651-B2 | Piperazine substituted azapine derivatives and uses thereof | ALAIRION, INC. (US) | 2021-06-29 | — | — | US | disclosed |
| US-20210114989-A1 | PIPERAZINE SUBSTITUTED AZAPINE DERIVATIVES AND USES THEREOF | Neumora Therapeutics, Inc. | 2021-04-22 | — | — | US | disclosed |
| US-10647693-B2 | Inhibitors of influenza virus replication, application methods and uses thereof | NORTH & SOUTH BROTHER PHARMACY INVESTMENT COMPANY LIMITED (HK) | 2020-05-12 | — | — | US | disclosed |
| US-20190194159-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-06-27 | — | — | US | disclosed |
| WO-2019024924-A1 | AMINE COMPOUND FOR INHIBITING SSAO/VAP-1 AND USE THEREOF IN MEDICINE | 广东东阳光药业有限公司 | 2019-02-07 | — | — | WO | disclosed |
| EP-0529395-A2 | Benzamide multidrug resistance reversing agents | Bristol-Myers Squibb Company (US) | 1993-03-03 | — | — | EP | disclosed |
| EP-0529386-A1 | Dibenz[B,F][1,4]oxazepin-11(10H)-ones for multidrug resistance reversing agents | Bristol-Myers Squibb Company (US) | 1993-03-03 | — | — | EP | disclosed |
| US-5173486-A | Adjuvant chemotherapy for cancer and tumor therapy | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-12-22 | — | — | US | disclosed |
| US-5173486-A | Adjuvant chemotherapy for cancer and tumor therapy | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-12-22 | — | — | US | disclosed |
| EP-0419861-A2 | Use of dibenz[b,f][1,4]oxazepin (and thiazepin)-11(10H)-ones and -thiones in the preparation of a pharmaceutical composition for the prevention or treatment of aids | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1991-04-03 | — | — | EP | disclosed |
| US-4888335-A | HYPOTENSIVE AGENTS | MCNEILAB, INC. (US) | 1989-12-19 | — | — | US | disclosed |
| EP-0054951-B1 | DIBENZ(B,F)(1,4)OXAZEPINE DERIVATIVES, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 1984-12-12 | — | — | EP | disclosed |
| US-4379150-A | Dibenz[b,f][1,4]oxazepine derivatives, process for preparing the same, and pharmaceutical compositions comprising the same | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1983-04-05 | — | — | US | disclosed |
| US-4002639-A | ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647693-B2 | Inhibitors of influenza virus replication, application methods and uses thereof | EIF2AK2, POLRMT, SNRPE | ALOX5 2950/4885MAPT 4259/4885L3MBTL1 3968/4885 |
| US-20190194159-A1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION, APPLICATION METHODS AND USES THEREOF | EIF2AK2, POLRMT, SNRPE | ALOX5 2950/4885MAPT 4259/4885L3MBTL1 3968/4885 |
| US-11046651-B2 | Piperazine substituted azapine derivatives and uses thereof | HTR2A, HTR5A, HTR2C | ALOX5 578/4885MAPT 3698/4885L3MBTL1 4534/4885 |
| US-20140045850-A1 | INHIBITORS OF HISTONE DEACETYLASE | HDAC1, HDAC11, HDAC3 | ALOX5 2621/4885MAPT 2336/4885L3MBTL1 610/4885 |
| US-20210114989-A1 | PIPERAZINE SUBSTITUTED AZAPINE DERIVATIVES AND USES THEREOF | HTR2A, HTR5A, HTR2C | ALOX5 578/4885MAPT 3698/4885L3MBTL1 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.