Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9095821 | 0.82 | ALDH1A1 (0.47) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL10706332 | 0.75 | ALDH1A1 (0.54) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL11413330 | 0.73 | CHRM2 (0.45) | LMNAKDM4EALDH1A1ALOX12CD274 | |
| SCHEMBL11410647 | 0.72 | ALDH1A1 (0.53) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL29288168 | 0.71 | HSD17B2 (0.41) | LMNAKDM4ETDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29288167 | 0.71 | HSD17B2 (0.41) | LMNAKDM4ETDP1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3673299 | 0.69 | ALDH1A1 (0.63) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL9978640 | 0.69 | KMT2A (0.34) | CRHR1KMT2A | |
| SCHEMBL9095902 | 0.68 | OPRK1 (0.39) | CD274KMT2A | |
| SCHEMBL4171219 | 0.67 | ALDH1A1 (0.52) | LMNAKDM4ECNR1ADRA1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516910-A | N--2--chlorobenzyl--2--oxo and n--2--chlorobenzyl--2,2--dioxo--1,2,3--oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2--c]pyridine derivatives therefrom | SYNTEX (U.S.A.) INC. (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0497695-B1 | N-2-chlorobenzyl-2-oxo and N-2-chlorobenzyl-2,2-dioxo-1,2,3-oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2-c]pyridine derivatives therefrom | SANOFI SA (FR) | 1994-12-14 | — | — | EP | disclosed |
| US-5342953-A | N-2-chlorobenzyl-2-oxo and N-2-chlorobenzyl-2,2-dioxo-1,2,3-oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2-c]pyridine derivatives therefrom | SYNTEX (U.S.A.) INC. (US) | 1994-08-30 | — | — | US | disclosed |
| EP-0497695-A1 | N-2-chlorobenzyl-2-oxo and N-2-chlorobenzyl-2,2-dioxo-1,2,3-oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2-c]pyridine derivatives therefrom | SANOFI (FR) | 1992-08-05 | — | — | EP | disclosed |