Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18322510 | 0.71 | ROCK2 (0.46) | OPRK1CYP1A2CYP2D6CYP2C19ROCK2 | |
| SCHEMBL20297332 | 0.71 | ROCK2 (0.46) | OPRK1CYP1A2CYP2D6CYP2C19ROCK2 | |
| SCHEMBL588144 | 0.68 | KDM4E (0.46) | ROCK2 | |
| SCHEMBL29442719 | 0.68 | TRPV3 (0.42) | ROCK2GAACD274 | |
| SCHEMBL22345793 | 0.68 | ROCK2 (0.36) | CYP1A2ROCK2CD274 | |
| SCHEMBL30850026 | 0.68 | TRPV3 (0.42) | ROCK2GAACD274 | |
| SCHEMBL22345791 | 0.68 | ROCK2 (0.36) | CYP1A2ROCK2CD274 | |
| SCHEMBL22345797 | 0.68 | TRPV3 (0.42) | ROCK2GAACD274 | |
| SCHEMBL20268384 | 0.68 | TRPV3 (0.42) | ROCK2GAACD274 | |
| SCHEMBL30850042 | 0.68 | ROCK2 (0.36) | CYP1A2ROCK2CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516910-A | N--2--chlorobenzyl--2--oxo and n--2--chlorobenzyl--2,2--dioxo--1,2,3--oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2--c]pyridine derivatives therefrom | SYNTEX (U.S.A.) INC. (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0497695-B1 | N-2-chlorobenzyl-2-oxo and N-2-chlorobenzyl-2,2-dioxo-1,2,3-oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2-c]pyridine derivatives therefrom | SANOFI SA (FR) | 1994-12-14 | — | — | EP | disclosed |
| US-5342953-A | N-2-chlorobenzyl-2-oxo and N-2-chlorobenzyl-2,2-dioxo-1,2,3-oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2-c]pyridine derivatives therefrom | SYNTEX (U.S.A.) INC. (US) | 1994-08-30 | — | — | US | disclosed |
| EP-0497695-A1 | N-2-chlorobenzyl-2-oxo and N-2-chlorobenzyl-2,2-dioxo-1,2,3-oxathiazolidine derivatives, their preparation and synthesis of thieno[3,2-c]pyridine derivatives therefrom | SANOFI (FR) | 1992-08-05 | — | — | EP | disclosed |