Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978634 | 0.83 | CRHR1 (0.30) | CRHR1 | |
| SCHEMBL23794996 | 0.77 | SLC6A4 (0.41) | KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2366778 | 0.77 | SLC6A4 (0.41) | KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16335384 | 0.77 | SLC6A4 (0.41) | KMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9094561 | 0.69 | LMNA (0.45) | KMT2ACRHR1 | |
| SCHEMBL11566355 | 0.68 | ABCB1 (0.38) | — | |
| SCHEMBL2366758 | 0.68 | KMT2A (0.40) | KMT2ACYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL28249834 | 0.66 | CYP3A4 (0.43) | CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL25890496 | 0.66 | CYP3A4 (0.43) | CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL22103844 | 0.65 | ALDH1A1 (0.39) | CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576515-B1 | Pyrazolecarboxamide derivatives and their use as microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2014-04-16 | — | — | EP | disclosed |
| US-8552049-B2 | Pyrazolecarboxamide derivatives and their use as microbiocides | Syngenta Corp Protection, LLC (US) | 2013-10-08 | — | — | US | disclosed |
| US-8552049-B2 | Pyrazolecarboxamide derivatives and their use as microbiocides | Syngenta Corp Protection, LLC (US) | 2013-10-08 | — | — | US | disclosed |
| US-8552049-B2 | Pyrazolecarboxamide derivatives and their use as microbiocides | Syngenta Corp Protection, LLC (US) | 2013-10-08 | — | — | US | disclosed |
| EP-2576515-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | Syngenta Participations AG (CH) | 2013-04-10 | — | — | EP | disclosed |
| US-20130072535-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072535-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072535-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-21 | — | — | US | disclosed |
| WO-2011147690-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011147690-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072535-A1 | PYRAZOLECARBOXAMIDE DERIVATIVES AND THEIR USE AS MICROBIOCIDES | HRH4, MRGPRX4, C3AR1 | KMT2A 3956/4885CYP1A2 727/4885CYP2D6 354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.