Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351897 | 0.90 | STAT3 (0.45) | STAT3STAT1MAPTBRD4HSD17B10 | |
| SCHEMBL1596068 | 0.90 | STAT3 (0.47) | STAT3STAT1KDM4EMAPTBRD4 | |
| SCHEMBL351526 | 0.88 | STAT3 (0.43) | STAT3STAT1MAPTBRD4HSD17B10 | |
| SCHEMBL1597373 | 0.88 | STAT3 (0.43) | STAT3STAT1MAPTKIF11BRD4 | |
| SCHEMBL6417535 | 0.87 | STAT3 (0.39) | STAT3STAT1KDM4EMAPTALDH1A1 | |
| SCHEMBL9234160 | 0.81 | STAT3 (0.36) | STAT3STAT1 | |
| SCHEMBL9094548 | 0.79 | STAT3 (0.46) | STAT3STAT1KMT2AMEN1KIF11 | |
| SCHEMBL5445020 | 0.79 | STAT3 (0.36) | STAT3STAT1 | |
| SCHEMBL13504831 | 0.78 | STAT3 (0.42) | STAT3STAT1KDM4EKMT2AMAPT | |
| SCHEMBL3125425 | 0.78 | STAT3 (0.49) | STAT3STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498710-A | PHOTOSENSITIZERS | HEALTH RESEARCH, INC. (US) | 1996-03-12 | — | — | US | disclosed |