Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 5/20 | 0.33 |
| ▸ | TOP1 | P11387 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYCS | P99999 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351897 | 0.97 | STAT3 (0.45) | STAT3STAT1BRD4TOP1MAPT | |
| SCHEMBL1597373 | 0.95 | STAT3 (0.43) | STAT3STAT1BRD4TOP1MAPT | |
| SCHEMBL351526 | 0.95 | STAT3 (0.43) | STAT3STAT1BRD4TOP1MAPT | |
| SCHEMBL9095058 | 0.90 | STAT3 (0.45) | STAT3STAT1BRD4MAPTALOX15 | |
| SCHEMBL5445020 | 0.85 | STAT3 (0.36) | STAT3STAT1 | |
| SCHEMBL6412535 | 0.84 | ABCG2 (0.45) | STAT3STAT1BRD4MAPTABCG2 | |
| SCHEMBL3125425 | 0.84 | STAT3 (0.49) | STAT3STAT1TOP1CYCS | |
| SCHEMBL6094135 | 0.82 | STAT3 (0.45) | STAT3STAT1TOP1 | |
| SCHEMBL5034725 | 0.82 | STAT3 (0.47) | STAT3STAT1TOP1ABCG2HSD17B10 | |
| SCHEMBL16673442 | 0.81 | STAT3 (0.44) | STAT3STAT1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420804-B2 | Formyl- and acetal-porphyrins bearing tripodal linking groups | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-04-16 | — | — | US | claimed |
| US-20110152515-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-06-23 | — | — | US | claimed |
| US-20090137795-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-05-28 | — | — | US | claimed |
| US-7501507-B2 | Route to formyl-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-03-10 | — | — | US | claimed |
| US-20050277770-A1 | condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-12-15 | — | — | US | claimed |
| US-8420804-B2 | Formyl- and acetal-porphyrins bearing tripodal linking groups | NORTH CAROLINA STATE UNIVERSITY (US) | 2013-04-16 | — | — | US | disclosed |
| US-20110152515-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-06-23 | — | — | US | disclosed |
| US-7919615-B2 | Route to formyl-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2011-04-05 | — | — | US | disclosed |
| US-20090137795-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-05-28 | — | — | US | disclosed |
| US-7501507-B2 | Route to formyl-porphyrins | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-03-10 | — | — | US | disclosed |
| US-20050277770-A1 | condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137795-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | PPOX, DHPS, FDPS | STAT3 3755/4885STAT1 3957/4885BRD4 3238/4885 |
| US-20110152515-A1 | NEW ROUTE TO FORMYL-PORPHYRINS | PPOX, ALAD, UROD | STAT3 4123/4885STAT1 4328/4885BRD4 3068/4885 |
| US-20050277770-A1 | condensing a 5-acetaldipyrromethane with a dipyrromethane-1,9-dicarbinol to produce a porphyrin having an acetal group substituted thereon at the 5 position; and then hydrolyzing said porphyrin to produce said 5-formylporphyrin | DHPS, NOTUM, DOHH | STAT3 4298/4885STAT1 4505/4885BRD4 3073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.