Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138643 | 0.87 | LMNA (0.33) | — | |
| SCHEMBL909791 | 0.86 | TSHR (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL6440852 | 0.77 | LMNA (0.38) | — | |
| SCHEMBL16308911 | 0.76 | TSHR (0.39) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL3683984 | 0.76 | ALDH1A1 (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL329061 | 0.75 | LMNA (0.33) | — | |
| SCHEMBL1225084 | 0.75 | — | — | |
| SCHEMBL12190455 | 0.75 | — | — | |
| Di(Hydroxyethyl)Ether SCHEMBL6171 | 0.74 | TSHR (0.77) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL9058372 | 0.74 | TSHR (0.77) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251038-B1 | SOLID DISPERSION, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR THE PRODUCTION OF BOTH | ASKA PHARM CO LTD (JP) | 2017-05-10 | — | — | EP | disclosed |
| US-8722094-B2 | Solid dispersion and pharmaceutical composition of the same, and production processes thereof | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20110020455-A1 | SOLID DISPERSION AND PHARMACEUTICAL COMPOSITION OF THE SAME, AND PRODUCTION PROCESSES THEREOF | ASKA PHARMACEUTICAL CO., LTD. | 2011-01-27 | — | — | US | disclosed |
| EP-2251038-A1 | SOLID DISPERSION, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND PROCESSES FOR THE PRODUCTION OF BOTH | ASKA Pharmaceutical Co., Ltd. (JP) | 2010-11-17 | — | — | EP | disclosed |