Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5725898 | 0.92 | MEN1 (0.39) | KMT2AMEN1POLBDHFRSLC6A3 | |
| SCHEMBL5725631 | 0.87 | NPSR1 (0.36) | KMT2AMEN1POLBSMN1; SMN2SLC6A2 | |
| SCHEMBL10803495 | 0.85 | MEN1 (0.37) | KMT2AMEN1POLBDHFRSLC6A2 | |
| SCHEMBL5726536 | 0.83 | DHFR (0.39) | KMT2AMEN1POLBDHFRSLC6A3 | |
| SCHEMBL9859794 | 0.82 | LTA4H (0.48) | KMT2AMEN1POLBLTA4HEPHX2 | |
| SCHEMBL10916857 | 0.82 | MEN1 (0.41) | KMT2AMEN1POLBDHFRSLC6A3 | |
| SCHEMBL8601010 | 0.82 | LMNA (0.46) | KMT2AMEN1HRH3CYP2D6LTA4H | |
| SCHEMBL10923422 | 0.79 | MEN1 (0.47) | KMT2AMEN1POLBRAB9ASLC6A3 | |
| SCHEMBL9860239 | 0.79 | MEN1 (0.43) | KMT2AMEN1POLBRAB9ADHFR | |
| SCHEMBL19556828 | 0.79 | DHFR (0.45) | KMT2AMEN1HRH3CYP2D6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491173-A | ESTROGENIC, ANTIESTROGENIC AGENTS, ANTITUMOR AGENTS | ORION-YHTYMA OY (FI) | 1996-02-13 | — | — | US | disclosed |