Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696283 | 0.86 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL9255827 | 0.84 | ALOX5 (0.40) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9101184 | 0.80 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL7481034 | 0.76 | ALOX5 (0.53) | ALOX5PTGS1PTGS2 | |
| SCHEMBL8630367 | 0.75 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9101868 | 0.75 | P2RX7 (0.37) | ALOX5 | |
| SCHEMBL8696312 | 0.72 | ALOX5 (0.41) | ALOX5 | |
| SCHEMBL1598547 | 0.70 | ALOX5 (0.51) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9027778 | 0.70 | ALOX5 (0.48) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9100023 | 0.69 | ALOX5 (0.45) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702680-A1 | 2-OXO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994029297-A1 | 2-OXO-1,2,3,4-TETRAHYDROQUINOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1994-12-22 | — | — | WO | disclosed |