SCHEMBL9100646

SCHEMBL9100646

C=Cc1ccc2c(c1)C(=O)c1ccccc1-2

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.48
RAB9A P51151 5/20 0.48
ALDH1A1 P00352 5/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
MAPK1 P28482 4/20 0.48
TP53 P04637 2/20 0.48
CYP3A4 P08684 2/20 0.48
ELANE P08246 1/20 0.48
TSHR P16473 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
CDC25B P30305 1/20 0.48
PTPRC P08575 5/20 0.47
S100A4 P26447 3/20 0.47
LMNA P02545 3/20 0.47
PLA2G1B P04054 3/20 0.47
ATG4B Q9Y4P1 3/20 0.47
APAF1 O14727 2/20 0.47
TDP2 O95551 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6385626 0.98 NPC1 (0.50) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL17183763 0.85 ALDH1A1 (0.48) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL19639115 0.84 MCL1 (0.49) ALDH1A1SMN1; SMN2MAPK1CYP3A4TDP1
SCHEMBL6253115 0.82 NPC1 (0.50) NPC1RAB9AALDH1A1SMN1; SMN2MAPK1
SCHEMBL19655043 0.81 BCL2 (0.56) RAB9AMAPK1TDP1MEN1KMT2A
SCHEMBL19655042 0.81 S100A4 (0.55) ALDH1A1S100A4MAOACES1USP8
SCHEMBL19655035 0.81 ELANE (0.60) MAPK1TP53ELANETDP1MEN1
SCHEMBL13070978 0.81 ALDH1A1 (0.36) ALDH1A1TP53TDP1S100A4BCL2
SCHEMBL9946541 0.81 ESR2 (0.67) NPC1RAB9AALDH1A1MEN1KMT2A
SCHEMBL19655041 0.81 ALDH1A1 (0.40) ALDH1A1CYP3A4MAOAUSP8USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4011266-A 2-VINYL-FLUORENONE AND DERIVATIVES THEREOF XEROX CORPORATION (US) 1977-03-08 US claimed
US-20210066734-A1 REDOX FLOW BATTERY SYSTEM DENSO CORPORATION (JP) 2021-03-04 US disclosed
US-5545760-A VAPOR PHASE OXIDATION OF THE CORRESPONDING FLUORENE THE DOW CHEMICAL COMPANY (US) 1996-08-13 US disclosed
EP-0005379-B2 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1986-06-04 EP disclosed
US-4552830-A UNSATURATED COMPOUND, FREE RADICAL-PRODUCING PHOTOINITIATOR FLUORA COLOR FORMER, PROTON DONOR DYNACHEM CORPORATION (US) 1985-11-12 US disclosed
US-4343885-A PHOTORESISTS DYNACHEM CORPORATION (US) 1982-08-10 US disclosed
EP-0005380-B1 PHOTOTROPIC PHOTOSENSITIVE COMPOSITIONS CONTAINING A FLUORAN COLORFORMER Dynachem Corporation (US) 1982-01-06 EP disclosed
EP-0005379-B1 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1981-12-23 EP disclosed
EP-0005379-A2 Photosensitive compositions containing carbonylic halides as activators Dynachem Corporation (US) 1979-11-14 EP disclosed
EP-0005380-A2 Phototropic photosensitive compositions containing a fluoran colorformer Dynachem Corporation (US) 1979-11-14 EP disclosed
US-4011266-A 2-VINYL-FLUORENONE AND DERIVATIVES THEREOF XEROX CORPORATION (US) 1977-03-08 US disclosed
US-4009151-A Polymers of 2-vinyl-fluorenone and derivatives thereof XEROX CORPORATION (US) 1977-02-22 US disclosed
US-4009151-A Polymers of 2-vinyl-fluorenone and derivatives thereof XEROX CORPORATION (US) 1977-02-22 US disclosed