SCHEMBL24974709

SCHEMBL24974709

CN(C(=O)NCCNC(=O)OC(C)(C)C)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 1/20 0.51
CKS1B P61024 1/20 0.50
SKP1 P63208 1/20 0.50
SKP2 Q13309 1/20 0.50
IDO1 P14902 1/20 0.48
BCHE P06276 1/20 0.46
DRD2 P14416 2/20 0.45
ADRA1A P35348 1/20 0.45
DRD3 P35462 1/20 0.45
MEN1 O00255 1/20 0.43
GAA P10253 1/20 0.43
KMT2A Q03164 1/20 0.43
AKT1 P31749 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
SIGMAR1 Q99720 1/20 0.41
CTSK P43235 1/20 0.41
KDM4A O75164 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23978843 0.83 CTSL (0.55) MALT1CKS1BSKP1SKP2IDO1
SCHEMBL5447593 0.81 PPIB (0.50) MALT1CKS1BSKP1SKP2IDO1
SCHEMBL24413752 0.81 MALT1 (0.49) MALT1CKS1BSKP1SKP2IDO1
SCHEMBL8354855 0.80 CYP3A4 (0.52) MALT1IDO1DRD2MEN1GAA
SCHEMBL29182078 0.80 KMT2A (0.48) MALT1CKS1BSKP1SKP2IDO1
SCHEMBL9100684 0.79 CKS1B (0.52) MALT1CKS1BSKP1SKP2IDO1
SCHEMBL15283620 0.77 CKS1B (0.50) MALT1CKS1BSKP1SKP2IDO1
SCHEMBL20266341 0.77 PKM (0.47) DRD2ADRA1ADRD3MEN1GAA
SCHEMBL22605044 0.77 ATM (0.58) MALT1IDO1BCHEMEN1GAA
SCHEMBL894822 0.77 ATM (0.58) MALT1IDO1BCHEMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572370-B2 CD16A binding agents and uses thereof BIOHAVEN THERAPEUTICS LTD. (US) 2023-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572370-B2 CD16A binding agents and uses thereof FCGR1A, FCGR2A, FCGR3B MALT1 497/4885CKS1B 1920/4885SKP1 4038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.