Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | THRB | P10828 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bepiastine SCHEMBL1815039 | 0.84 | LMNA (0.64) | LMNATHRBTP53MAPTPOLB | |
| Bepiastine SCHEMBL29560445 | 0.84 | LMNA (0.64) | LMNATHRBTP53MAPTPOLB | |
| SCHEMBL9101431 | 0.82 | LMNA (0.58) | LMNATHRBTP53MAPTPOLB | |
| SCHEMBL8791051 | 0.76 | BRD4 (0.51) | LMNATHRBTP53MAPTMEN1 | |
| SCHEMBL9369777 | 0.74 | BRD4 (0.50) | LMNATP53MAPTMEN1KMT2A | |
| SCHEMBL8790081 | 0.73 | ALDH1A1 (0.71) | TP53MAPT | |
| SCHEMBL9431569 | 0.73 | ALDH1A1 (0.57) | — | |
| SCHEMBL8301100 | 0.73 | ALDH1A1 (0.50) | LMNATHRBTP53MAPTMEN1 | |
| SCHEMBL8791127 | 0.72 | BRD4 (0.48) | LMNATHRBTP53MAPTMEN1 | |
| SCHEMBL9370046 | 0.72 | BRD4 (0.48) | LMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550122-A | INHIBIT REVERSE TRANSCRIPTASE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1996-08-27 | — | — | US | disclosed |
| EP-0415303-B1 | Pyrido [2,3-b][1,5]benzoxazepin (and thiazepin)-5(6H)-ones and -thiones and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMA (US) | 1995-12-13 | — | — | EP | disclosed |
| EP-0415303-A2 | Pyrido [2,3-b][1,5]benzoxazepin (and thiazepin)-5(6H)-ones and -thiones and their use in the prevention or treatment of HIV infection | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1991-03-06 | — | — | EP | disclosed |